Get Directions Call Us HSHS Holy Family Heart Care 200 Healthcare Dr | Greenville, Illinois 62246 (618)-664-1230 Whether it is an emergency or a planned procedure, HSHS Holy Family Hospital and the Prairie Heart Institute provide nationally recognized heart care close to home. Plan Your Visit To HSHS Holy Family Heart Care With patient-first care you've come to expect from the HSHS doctors and nurses, you have the comfort of knowing we are using our hearts to care for yours. p Hours of Operation 24/7 s Learn More Learn more about the HSHS Holy Family Heart Care. How can we help you today? Select Select Women's Health Cardiovascular Cancer Center Submit