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Infusion Services

Outpatient services for chemotherapy, blood infusions, dressing changes and antibiotics with HSHS St. John's Hospital Infusion Center of O'Fallon

Smiling nurse preparing infusion therapy for a female patient

NOTE: The management of this outpatient infusion services location was renamed effective June 24, 2024

HSHS St. John’s Hospital Infusion Center of O’Fallon is located in O’Fallon, Illinois, on the campus of HSHS St. Elizabeth’s Hospital at 3 St. Elizabeth’s Blvd. The Center is located on the 2nd floor of the Health Center. 

Information for patients at this location:

  • Patients can register directly at the Infusion Center. They DO NOT need to visit the main registration desk at St. Elizabeth’s Hospital. 
  • Phone number: 618-607-5700. Fax Number: 618-607-5701

It is recommended that you contact your insurance company as coverage may be different for services provided in a hospital outpatient department location.

We offer a wide range of infusion therapies to treat a variety of conditions. A physician referral is required. Our therapies include: 

Our Specialties

  • Anti-Infective Therapy (Antifungal, Antiviral)
  • Aranesp
  • Biological response modifiers (tx rheumatoid arthritis and other conditions)
  • Blood products such as platelets, RBCs, and/or plasma
  • Chemotherapy
  • Epogen/Procfit
  • Haldol
  • Hemophilia Factor Products
  • IM SQ
  • Immunoglobulin Therapy
  • Immunomodulators
  • Injections
  • Injectafer
  • Intravenous Antibiotics
  • Invega
  • IV antiemetics for nausea and vomiting
  • IV Hydration therapy
  • Rabies
  • Xolair

Other services include:

  • Declotting/Maintenance VADs, including Central Lines
  • Placement and maintenance of peripheral inserted central catheter (PICC) lines
  • Port-a-Cath access and maintenance


For a copy of our pre-printed order sheet or ordering criteria, please call 618-234-2120, ext. 25892.

Please fax orders and demographics to 618-641-5452.