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    1 St Elizabeth's Blvd
    O'Fallon, Illinois 62269
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HSHS St. Elizabeth's Hospital, O'Fallon, Illinois

Cancer Care at HSHS St. Elizabeth's Hospital

Cancer Care

Treating the whole patient from prevention to diagnosis, treatment and recovery
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Convenient Care at HSHS St. Elizabeth's Hospital

Convenient Care

A better, faster and more comprehensive approach to patients needing quality care for unexpected illnesses, minor accidents or work-related injuries. No appointment necessary, walk-in at your convenience.
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Heart Care at HSHS St. Elizabeth's Hospital

Heart Care

From high cholesterol to high blood pressure and comprehensive heart and vascular care, our team will be right by your side with expert, compassionate care focused on getting you back to those who matter most.
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HSHS St. Elizabeth's latest news

HSHS Home Care Butterfly Release Ceremony

Butterfly Release Ceremonies Planned Across Southern Illinois

May 07, 2026
The community is invited to celebrate loves ones at memorial butterfly release ceremonies in Greenville, O'Fallon, Highland and Breese
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Runner leaning down to tie shoe

Running Performance Program Returns to Help Runners of All Experience Levels

May 04, 2026
HSHS St. Elizabeth's re-launches program to help improve efficiency and reduce risk of injury for runners
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Healthcare Bootcamp for High School students set for Summer 2026

Healthcare Bootcamp for High School students set for Summer 2026

April 16, 2026
Students are invited to apply by May 2
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